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Barry, OppHub America Desk · · Source: prnewswire-financial

Vaderis Therapeutics Announces Oversubscribed $152 Million Series B Financing and Initiati

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Vaderis Therapeutics Announces Oversubscribed $152 Million Series B Financing and Initiation of the Global Phase 3 HEROIC Study of Engasertib for Hereditary Hemorrhagic Telangiectasia USA - English USA - English News provided by Vaderis Therapeutics AG Aug 11, 2026, 07:00 ET Share this article Share to X Share this art

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Vaderis Therapeutics Announces Oversubscribed $152 Million Series B Financing and Initiati
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on of the Global Phase 3 HEROIC Study of Engasertib for Hereditary Hemorrhagic Telangiectasia USA - English USA - English News provided by Vaderis Therapeutics AG Aug 11, 2026, 07:00 ET Share this article Share to X Share this article Share to X $152 million Series B financing by private placement to select investors, co-led by Life Sciences at Goldman Sachs Alternatives and TCGX, with participation from Omega Funds, EQT Life Sciences, Perceptive Advisors, Kalehua Capital, and existing investors Medicxi and Droia Provides the company with capital needs through potential U.S. regulatory approval of engasertib Marks the company's transition into pivotal-stage development with initiation of the global Phase 3 HEROIC study evaluating engasertib, a once daily oral medication, in patients with moderate-to-severe hereditary hemorrhagic telangiectasia (HHT) BASEL, Switzerland and LINCOLNSHIRE, Ill. 11, 2026 /PRNewswire/ -- Vaderis Therapeutics, a clinical-stage biopharmaceutical company focused on developing targeted therapies for rare vascular diseases, today announced the closing of a private $152 million Series B financing and initiation of HEROIC, the company's global Phase 3 clinical study evaluating engasertib (VAD044) in patients with hereditary hemorrhagic telangiectasia (HHT). Together, these milestones mark a significant step forward in the development of engasertib, an investigational oral allosteric AKT inhibitor. Engasertib is positioned to become the first approved therapy specifically developed for people living with HHT, a rare genetic vascular disorder that currently has no approved treatment options worldwide.

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Snapshot date: August 11, 2026 at 7:10 AM ET

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Story → money map

biotech venture financing

A private medical company raised a large amount of money to test a new drug in final-stage clinical trials. Major investment banks helped fund the deal, showing that professional investors still see strong potential in medical research.

What changed

Vaderis Therapeutics closed a $152 million Series B financing round and launched a global Phase 3 clinical trial for engasertib.

Who wins / who loses

Specialized biotech investors and participating private equity funds benefit from clinical progress, while broader retail investors lack direct access to this private company.

Time horizon

Think in terms of the next few months.

Confidence & best fit

low confidence · Long-term investor

Low confidence → prefer ETFs and “Watch,” not rushing into one stock.

Quick glossary: Watch = track, don’t buy yet · Build slowly = only if it fits your plan · Protect = reduce risk · ETF = a basket of stocks (often safer than one company)
Safer theme exposure (ETFs)

Baskets that own the theme without betting on one company.

  • $XBI A basket of biotech stocks that tracks how the wider medical research sector is performing.

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  • $IBB A broad fund containing many different medical and drug development companies.
Single stocks (higher risk)

Primary = closest to the story · Peers = same industry · Second-order = knock-on effects · Avoid = looks related but may be a trap

Primary

  • $GSWatch — track, don’t rush

    Goldman Sachs helped lead the funding round for the private medical company.

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Peer

  • $JPMWatch — track, don’t rush

    Other big banks monitor large private health investments and capital raising trends.

    View $JPM chart → · End-of-day delayed data

  • $BACWatch — track, don’t rush

    Large banks track how much money venture capitalists are spending on new medical treatments.

    View $BAC chart → · End-of-day delayed data

Options (education only)

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Beginners should skip options for this story since the main company raising money is private and not traded on the stock market.

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Income / OppHub America angle

Not a trade tip — ways to use the insight outside the market.

  • Monitor private equity and venture capital secondary markets for late-stage biotech co-investment opportunities.
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What would break this thesis
  • Broader macroeconomic tightening restricting venture capital deployment across the life sciences sector.
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Based on reporting from prnewswire-financial.

Informational and educational only — not investment, financial, or legal advice. Disclosure

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